Publications & talks

2026

• Bacteria deliver a microtubule-binding protein into mammalian cells to promote colonization

  Costello MS, Neumann B, Raimondi MW, … Torres JA, Holznecht N, … Goulding CW, Gonen S, Hayes CS.

  Science·2026DOI ↗PubMed ↗

• Real-world outcomes of managing ADPKD using a medical food as part of a nutrition and lifestyle program

  Muensterman E, Torres JA, Weimbs T.

  Frontiers in Nutrition·2026DOI ↗PubMed ↗

2024

• β-Hydroxybutyrate recapitulates the beneficial effects of ketogenic metabolic therapy in polycystic kidney disease

  Torres JA, Holznecht N, Asplund DA, Kroes BC, Amarlkhagva T, Haeffner MM, … Thangaraju M, Weimbs T.

  iScience·2024DOI ↗PubMed ↗

• Trigger warning: how modern diet, lifestyle, and environment pull the trigger on ADPKD progression

  Messing M, Torres JA, Holznecht N, Weimbs T.

  Nutrients·2024DOI ↗PubMed ↗

2023

• Feasibility and impact of ketogenic dietary interventions in polycystic kidney disease: KETO-ADPKD — a randomized controlled trial

  Cukoski S, Lindemann CH, Arjune S, … Torres JA, … Grundmann F, Müller R-U.

  Cell Reports Medicine·2023DOI ↗PubMed ↗

• A combination of β-hydroxybutyrate and citrate ameliorates disease progression in a rat model of polycystic kidney disease

  Torres JA, Holznecht N, Asplund DA, Amarlkhagva T, Kroes B, Rebello J, Agrawal S, Weimbs T.

  Am J Physiol-Renal Physiol·2023DOI ↗PubMed ↗

2022

• Ren.Nu, a dietary program for individuals with ADPKD implementing a sustainable, plant-focused, kidney-safe, ketogenic approach

  Bruen DM, Kingaard JJ, Munits M, Paimanta CS, Torres JA, Saville J, Weimbs T.

  Kidney and Dialysis·2022DOI ↗

• Pharmacological effects of panduratin A on renal cyst development in in vitro and in vivo models of polycystic kidney disease

  Tonum K, Srimai N, Chabang N, Fongsupa S, Tuchinda P, Torres JA, Weimbs T, Soodvilai S.

  Int J Molecular Sciences·2022DOI ↗PubMed ↗

2021

• Ketogenic dietary interventions in ADPKD — a retrospective case series study: first insights into feasibility, safety and effects

  Strubl S, Oehm S, Torres JA, Grundmann F, Haratani J, Decker M, Vuong S, et al.

  Clinical Kidney Journal·2021DOI ↗PubMed ↗

2020

• STAT signaling in polycystic kidney disease

  Strubl S, Torres JA, Spindt AK, Pellegrini H, Liebau MC, Weimbs T.

  Cellular Signalling·2020DOI ↗PubMed ↗

2019

• Ketosis ameliorates renal cyst growth in polycystic kidney disease

  Torres JA, Kruger S, Broderick C, Amarlkhagva T, Agrawal S, Dodam JR, Mrug M, Lyons LA, Weimbs T.

  Cell Metabolism·2019DOI ↗PubMed ↗

• Crystal deposition triggers tubule dilation that accelerates cystogenesis in polycystic kidney disease

  Torres JA, Rezaei M, Broderick C, Lin L, Wang X, Hoppe B, Cowley BD Jr, Savica V, Torres VE, Khan S, Holmes RP, Mrug M, Weimbs T.

  J Clinical Investigation·2019DOI ↗PubMed ↗

2018

• Identification of targets of interleukin-13 and STAT6 signaling in polycystic kidney disease

  Olsan EE, West JD, Torres JA, Doerr N, Weimbs T.

  Am J Physiol-Renal Physiol·2018DOI ↗PubMed ↗

• Emerging targeted strategies for the treatment of autosomal dominant polycystic kidney disease

  Weimbs T, Shillingford J, Torres JA, Kruger S, Bourgeois B.

  Clinical Kidney Journal·2018DOI ↗PubMed ↗

Patent

• Methods and compositions for supporting renal health

  Inventors: Weimbs T, Torres J, Thangaraju M.

  US Patent 11,013,705·2021